Peptides / Supplements

Powerful Amino-Acid Structures that Enhance Your Body’s Normal Biological Function.

Peptides are short chains of amino acids that perform many important functions in the body. Unlike synthetic drugs, peptides work by mimicking the body’s biological processes, making them both highly effective and well-tolerated. Peptides are designed to address specific issues like building muscle, burning body fat, skin rejuvenation, sexual enhancement, stress reduction, immunity boosting, inflammation reduction, and increased healing and recovery from injuries.

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Sermorelin (Lean Muscle Mass, Fat Loss, Improved Metabolic Profile):
Sermorelin is a growth hormone releasing hormone (GHRH) naturally produced by the brain. Its function is to encourage the pituitary gland to produce and secrete human growth hormone (HGH). Sermorelin is not a growth hormone by itself, but instead a growth hormone secretagogue, a separate hormone that stimulates the production of human growth hormone (HGH). By promoting HGH production this helps regulate body composition and facilitates muscle and bone growth and is required to maintain healthy brain and organ tissue.

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How do Sermorelin levels relate to age?
The human body produces the highest amounts of Sermorelin during puberty, leveling off in their twenties, thirties and forties. Older men tend to be more likely to suffer from low levels of Sermorelin as the aging process slows down the body’s production of the hormone.

What happens when Sermorelin levels are low?
As men age, they will begin the experience adult-onset growth hormone deficiency, a phenomenon characterized by relative increase in fat mass and a commensurate decrease in muscle mass. They can also suffer from low energy levels, anxiety, and depression. Also, they may have maladjusted lipid levels, raising levels of LDL cholesterol and triglycerides. Many metabolic changes begin to occur which can lead to greater risk of heart disease, diabetes, and metabolic syndrome.

What are the effects of Sermorelin therapy?
Increased energy, improved mood, memory and cognition levels. It also helps lean muscle mass and fat loss helping improve body composition. Its broader health benefits include lower blood pressure and lower cholesterol facilitating overall better health.

(HGH) Human Growth Hormone (Cell Growth, Regeneration, and Cellular Reproduction):

Human Growth Hormone (HGH) also known as Somatotropin, is a peptide hormone secreted by the pituitary gland. It plays a crucial role in growth, cell regeneration, and tissue repair. Growth hormone is primarily produced in the growth stage of life, peaking at puberty, and then slowly declining as we age.

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What are the signs you might be experiencing growth hormone deficiency?
More body fat, particularly around the waist, reduced bone mass, struggling to build muscle mass, feeling anxious or depressed, exhaustion or fatigue, and sensitivity to temperatures.

What are some of the benefits of HGH treatment?
Some of the benefits include increased muscle mass, improved mood and mental health, increased energy levels, better quality sleep, increased libido, lower cholesterol and body fat, better immune system function, and faster recovery from injuries and wounds.

(HCG) Human Chorionic Gonadotropin (Fertility, balancing hormones, preventing testicular atrophy):
HCG is a peptide hormone, specifically a glycoprotein, produced primarily by the placenta during pregnancy. It consists of two polypeptides subunits ( alpha and beta) linked together, with sugar molecules attached, making it a glycoprotein. HCG play a role in early pregnancy by signaling the corpus luteum in the ovary to continue producing progesterone to support fetal development also stimulates Testosterone production in the fetal testes and is used to trigger ovulation in certain hormonal conditions.

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What role does HCG play in fertility?
Beyond pregnancy, HCG is used in fertility treatments to induce ovulation in women and help increase sperm production in men with hormonal deficiencies.

What happens to normal testosterone production when men use TRT?
Exogenous testosterone supplementation can suppress the body’s natural production of testosterone by inhibiting the hypothalamic-pituitary-gonadal (HPG) axis. This happens because the hypothalamus reduces the release of (GnRH) gonadotropin-releasing hormone which in turn decreases the release of (LH) luteinizing hormone and (FSH) follicle stimulating hormone because the external testosterone signals to the hypothalamus to reduce the release of these hormones. When these hormones are suppressed, testicular function declines, leading to testicular atrophy ( shrinkage) and reduced fertility.

How can HCG help men while using TRT?
HCG is structurally similar to the hormone LH and mimics it’s action by binding to the same receptors on the Leydig cells. When administered stimulates the testes to continue producing endogenous testosterone and helps maintain testicular size and function, even in the presence of exogenous testosterone’s helps maintain the body’s normal testosterones production and helps prevent testicular shrinkage and improves testicular function while using TRT.

PT-141 (Sexual Enhancement):
Also known as bremelanotide, PT-141 works by stimulating the melanocortin receptors in the brain, which are involved in sexual arousal, increased sexual desire, and physical response without affecting the cardiovascular system

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What is PT-141 used for?
PT-141 is approved to treat hypoactive sexual desire disorder in premenopausal women. It can be used for off-label use for men for libido and enhanced erections.

What are some of the other effects of PT-141?
Some of the other effects include increased physical arousal and genital circulation, improved sexual performance, elevated mood, enhanced metabolism, and improved lean muscle mass.

What are the common side effects of PT-141?
Some of the common side effects include flushing, headaches, nausea, irritation, reddening at the injection site.

Glutathione (Detoxification, Immune Support, Skin Support, Anti-Aging)

Glutathione is a tripeptide composed of three amino acids (glutamine, cysteine, and glycine). It is a powerful antioxidant naturally produced by the liver, crucial for preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxidases.

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What happens to the body’s Glutathione levels as we age?
As we age our glutathione levels begin to decline. Glutathione levels in the body many be reduced for a number of reasons, including poor nutrition,enviromental toxins,and oxidative stress.

What are the uses of Glutathione?
Glutathione is often referred to as the master antioxidant and supports detoxification, immune system support, nuerological support,and serves as key co-factor in important energy production cycles within the body. Other uses include cosmetic uses for skin lightening,anti-aging,and improved skin elacticity.

What are the benefits of Glutathione?
Glutathione helps reduce oxidative stress that can lead to chronic disease. This typically occurs when there is an imbalance between the production of free radicals and the body’s ability to fight them off.Levels of oxidative stress that are too high may be a precursor to multiple diseases such as diabetes,cancer,and rheumatoid arthritis.

How is Glutathione adminsitered?
Glutathione can be administered orally, subcutaneously,intramuscularly, or via I.V. administration depending on the treatment regimen and goals the patient wants to achieve.

(NAD+) Nicotinamide Adenine Dinucleotide (Energy production, cellular repair, anti-aging):
NAD+ is not a traditional peptide but rather a coenzyme derived from vitamin B3(niacin). It’s a small molecule composed of two nucleotides linked by their phosphate groups, not a chain of amino acids like peptides. However, it’s often discussed in the context of cellular health alongside peptides. NAD+ plays a critical role in energy metabolism and cellular function by acting as an electron carrier in redox reactions.

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What happens to NAD+ levels as we age?

NAD+ levels naturally decline with age due to reduced synthesis and increased consumption by enzymes ( PARP’s and CD38). This drop in NAD+ levels is linked to metabolic slowdown, reduced DNA repair, and increased age-related conditions.

Is NAD+ only important for energy production?
NAD+ has broader roles besides energy metabolism, it’s vital for DNA repair, gene expression, and cellular signaling by activating enzymes called Sirtuins and PAPRs. By using NAD+ or it’s precursors (NMN) nicotinamide mononucleotide or ( NR) nicotinamide riboside, these can help boost NAD+ levels aiming to combat aging, improve metabolic health, and enhance cellular resilience.

How often do I need to supplement NAD+ to notice a difference?
Most studies and supplement protocols recommend daily intake of NAD+ precursors because NAD+ has a relatively short half-life in the body (hours to a day), and consistent supplementation helps maintain elevated levels. Using a protocol with intravenous or injectables along with oral supplementation will raise levels on a more consistent basis.

Non-Peptides that Complement
or Enhance the Effects of Peptide Treatment

When considering peptide therapy, it’s essential to be aware of several non-peptide molecules that can complement or enhance the effects of peptide treatments.

More About Supplements that Compliment Peptiptide Therapy

Vitamins and Minerals:

Vitamin D
Plays a role in calcium metabolism and can influence muscle function and immune response, potentially enhancing the effects of peptides that support muscle health or immunity.
Magnesium
Important for muscle function, nerve transmission, and energy production. It can work synergistically with peptides like those targeting growth hormone release.
Zinc
Essential for immune function, wound healing, and DNA synthesis, which can complement treatments aimed at regeneration or recovery.

Amino Acids:

L-Arginine and L-Lysine

These amino acids can stimulate growth hormone release and are often used in conjunction with GHRH or GHRP peptides.
L-Carnitine

Can enhance fat metabolism, potentially complementing peptides focused on weight management or muscle growth.

Coenzymes and Enzymatic Cofactors:

Biotin (B7)
Helps facilitate carboxylation reactions, such as fatty acid synthesis and gluconeogenesis which are crucial steps for converting carbohydrates, fats, and proteins into usable energy and synthesizing fatty acids, which are the building blocks for cell membranes and hormones.
B Vitamins

Particularly B6, B9 (folate), and B12, which are coenzymes in methylation processes, impacting DNA repair and neurotransmitter function.

Hormones and Hormone Precursors:

Melatonin
Important for sleep regulation, which can be critical for recovery and hormone balance in peptide therapy.

DHEA (Dehydroepiandrosterone)
A precursor to sex hormones, which might be considered for its potential in anti-aging protocols alongside peptides.

Antioxidants:

Alpha-Lipoic Acid

An antioxidant that can recycle other antioxidants like vitamin C and glutathione, enhancing the body’s defense against oxidative stress
Coenzyme Q10
Vital for mitochondrial function and energy production, which could support therapies aimed at cellular health.

Fatty Acids:

Omega-3 Fatty Acids
These anti-inflammatory fats can support joint health, cognitive function, and heart health, which might be beneficial in comprehensive health strategies involving peptides.

Herbal Extracts:

Ashwagandha
An adaptogen that can help manage stress, potentially enhancing recovery and hormone balance.
Turmeric (Curcumin)

Known for its anti-inflammatory properties, it might complement peptides aimed at reducing inflammation.

Pharmacological Agents:

It’s crucial to consider how medications like statins, beta-blockers, or steroids might interact with peptide therapies, potentially affecting outcomes or requiring dose adjustments.

When integrating these non-peptides into a peptide therapy protocol, it’s vital to:

Consult with Healthcare Professionals
A medical expert should oversee the combination of peptides with other supplements or medications to avoid interactions or counterproductive effects.
Monitor Health Markers
Regular blood work or other diagnostic tests might be necessary to track how these non-peptides influence health outcomes alongside peptide treatments.
Consider Individual Health Needs
Personal health conditions, goals, and responses vary, so what works for one person might not suit another. Remember, the synergy between peptides and other compounds can be powerful, but it requires careful management to ensure safety and efficacy.

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